Mitochondrial Genome NGS Panel

Test Description | CPT Codes

Test Description

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Test Description

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Order Options

Sequencing (included)

Del/Dup (included)

Genes

MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, MT-RNR1, MT-RNR2, MT-TA, MT-TC, MT-TD, MT-TE, MT-TF, MT-TG, MT-TH, MT-TI, MT-TK, MT-TL1, MT-TL2, MT-TM, MT-TN, MT-TP, MT-TQ, MT-TR, MT-TS1, MT-TS2, MT-TT, MT-TV, MT-TW, MT-TY ( 37 genes )

Coverage:

99% at 1000x

Specimen Requirements:

Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request)

Test Limitations:

All sequencing technologies have limitations. This analysis is performed by PCR amplification of mitochondrial DNA and Next Generation Sequencing (NGS). This analysis is designed to examine all 37 mtDNA genes and utilizes overlapping primer sets to cover all 16,569 nucleotides. This assay has been validated for the detection of mitochondrial DNA heteroplasmy at a minimum level of 2-5%. This assay is not designed or validated for the detection of mutations occurring in nuclear-encoded genes.

CPT Codes:

CPT Code

81401, 81403, 81479x2

NOTE: The CPT codes listed on the website are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are provided here for the convenience of our clients. Clients who bill for services should make the final decision on which codes to use.