Pmcdx Cancer Panels cover 127 genes associated with potential risk for hereditary cancer syndromes. These panels include well-established cancer-related genes as well as candidate genes with newly discovered association with cancer but may have reduced or unclear risk. Hereditary cancer syndromes with complex presentations may benefit from more comprehensive testing. Pmcdx Cancer Panels maximize the chance of identifying disease-causing variants and provide an extensive review of potential cancer risks from additional candidate genes.