Endocrine& Metabolic PGx Test Panel
CYP2D6, ATM, FII, FV, MTHFR, CYP2C9, CYP3A4, CYP3A5
| Medication |
Gene |
| Metformin |
ATM |
| Estrogen-containing oral contraceptives |
FV, FII, MTHFR |
| Eliglustat |
CYP2D6 |
| Saxagliptin |
CYP3A4, CYP3A5 |
| Glimepiride, Gliclazide, Glibenclamide, Tolbutamide |
CYP2C9 |
Frequency of Cytochrome P450 (CYP2D6, CYP2C9) Metabolizer Types in the population
| Cytochrome |
Poor metabolizer |
Intermediate metabolizer |
Normal metabolizer |
Rapid or ultra-rapid metabolizer |
| CYP2D6 |
4-7% |
9-35% |
50-90% |
2-3% |
| CYP2C9 |
3% |
30% |
68% |
N/A |
